Accelerate Thermogenesis, Enhance Caloric Expenditure, and Optimize Metabolism: The Multifaceted Benefits of Bodybuilding.com’s Signature Shred
BBCOM Editors
January 10, 2025
Why Choose Bodybuilding.com’s Signature Shred?
Signature Shred is an advanced pre-workout supplement engineered to augment thermogenesis, boost calorie burning, and support fat loss. Its science-backed formulation comprises 1,500 mg of total carnitine, 1,000 mg of conjugated linoleic acid (CLA) powder, 7,500 mg of Garcinia cambogia extract, 200 mg of natural caffeine derived from coffee, and 40 mg of Aframomum melegueta extract—each ingredient selected to target key pathways in energy metabolism and body composition.
Ingredient Breakdown
Carnitine Complex
Carnitine is endogenously synthesized by the kidneys and liver to facilitate mitochondrial energy production. Unused carnitine is stored in skeletal muscle, heart, and brain for subsequent use. Dietary sources include red meat, dairy products, avocados, and soybeans; however, suboptimal intake—common in individuals with poor diets—can compromise fat metabolism. Severe carnitine deficiency may manifest as muscular weakness, cramps, fatigue, or hypoglycemia.
Signature Shred delivers 1,500 mg of carnitine across three bioavailable forms to maximize benefits:
L-carnitine fumarate: Combines carnitine with fumaric acid to directly modulate the Krebs cycle, enhancing energy availability.
Acetyl-L-carnitine hydrochloride: A water-soluble salt that crosses the blood-brain barrier, amplifying carnitine’s cognitive effects.
Weight Loss and Fat Metabolism Support
Carnitine facilitates the conversion of fat to energy, making it a valuable adjunct for weight management, fat oxidation, and energy optimization. Meta-analyses confirm that daily doses of 1,500 mg or more maximize weight and fat loss in adults.
Energy and Exercise Performance Enhancement
Research demonstrates that carnitine supplementation improves exercise performance, increases muscle mass, reduces post-exercise soreness, and enhances cognitive function—particularly in vegetarians, overweight individuals, and older adults.
Cognitive and Mental Health Benefits
Emerging evidence links carnitine—especially acetyl-L-carnitine—to improved cognitive function, mood stabilization, and broader brain health.
Conjugated Linoleic Acid (CLA)
CLA is a fatty acid found in beef and dairy products that promotes fat metabolism, improves insulin sensitivity, and alters body composition. While the exact mechanistic basis for its efficacy remains incompletely elucidated, clinical studies show CLA supplementation reduces fat accumulation, delays type 2 diabetes onset, and supports bone and immune function. When combined with structured exercise, CLA reduces body fat while preserving or increasing lean muscle mass—effectively improving body composition by prioritizing stored fat for energy.
Garcinia Cambogia Extract
Derived from the rind of the Garcinia cambogia fruit, this extract contains hydroxycitric acid (HCA), a compound that supports appetite control and weight management by elevating serotonin levels and promoting satiety. HCA may also inhibit de novo fat synthesis from carbohydrates. Preliminary research supports its use for short-term weight loss, making it a useful tool for craving management and fat production limitation.
Natural Caffeine (Robusta Coffee Bean-Sourced)
Signature Shred’s caffeine is extracted exclusively from robusta coffee beans, providing 200 mg—equivalent to a standard cup of coffee. Caffeine is a well-documented ergogenic aid:
Performance: Enhances aerobic/anaerobic capacity, muscular endurance, power output, high-intensity interval training (HIIT) performance, and fatigue resistance.
Cognition: Stimulates the central nervous system to improve focus, motivation, and reaction time.
Metabolism: Promotes fat oxidation, thermogenesis, and caloric expenditure.
Caffeine is safe and effective for supporting weight loss goals.
Aframomum Melegueta (CaloriBurn GP®)
CaloriBurn GP® is a patented form of Aframomum melegueta (grains of paradise), a West African spice containing the bioactive constituent 6-paradol. This compound enhances calorie expenditure and thermogenesis by activating brown adipose tissue (BAT)—a metabolically active tissue that increases resting metabolic rate and fat loss. Animal studies link 6-paradol to improved blood sugar regulation, reduced cravings, and enhanced energy. A human trial found that a single 40 mg dose increased whole-body energy expenditure via BAT activation.
Key Takeaways
Signature Shred’s synergistic blend—combining CLA, Garcinia cambogia extract, and CaloriBurn GP®—is designed to deliver sustained energy, enhanced fat metabolism, and optimal calorie expenditure. Backed by scientific evidence, this formulation supports fat loss, muscle retention, and the achievement of a lean, balanced body composition.
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